Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003o027 | Oral Communications 3: Environmental and programming effects on reproduction | SRF2016

Androgen causes whitening of brown adipose tissue: Implications for PCOS

Lerner Avi , Kewada Drashti , Ahmed Ayan , Okolo Anthony , Christian Mark , Hardy Kate , Franks Stephen

Polycystic ovary syndrome (PCOS) is a common endocrinopathy that is associated with hyperandrogenism- and an adverse metabolic profile including obesity and insulin resistance. Women with PCOS and raised androgen levels exhibit reduced postprandial thermogenesis and this is thought to predispose women with PCOS to weight gain (Robinson et al., 1992, Clin Endocrinol 36: 537–543). Brown adipose tissue (BAT) is important in the dissipation of energy in the form of heat and c...